Selected region : West
Date: : 24th Mar 2017

Current Studies:

The GLUT4 Study: The Importance of Abnormalities of Glucose Transport in Human Muscle in Type 2 Diabetes. University of Glasgow

Type 2 diabetes is a significant and increasing worldwide health problem. There are around 4.5 million people living with diabetes in the UK and this number is steadily increasing. One of the major risk factors for developing adult-onset diabetes is reduced ability of muscles to respond to the hormone insulin and take up sugar from the blood. This is called 'insulin resistance'.

The aim of this study is to understand the underlying abnormalities that occur within the muscles of people with type 2 diabetes. This will involve taking a small sample of muscle from the thigh of people with and without diabetes, and analysing these samples in the laborotary to identify differences in levels or function of key proteins.

The GoDARTS Study: Genetics of Diabetes Audit and Research in Tayside and Scotland.

This study wants to understand the role our genes, and other biological markers, play in developing and managing diabetes. By conducting this research it will hopefully provide some answers to some of the following questions surrounding the disease; why do some people develop the disease and others don't; why does medication work for some groups of patients with diabetes and not for others and why do some people develop the complications associated with diabetes and others don't.

The other aim of this study is to look at Metformin, which is one of the most commonly used drugs to treat type 2 diabetes. It can also be used in the treatment of type 1 diabetes in conjunction with insulin therapy. Metformin has been on the market for over 60 years yet its mechanism of action is not fully understood. Some patients respond well to the treatment and encounter very little problems, whilst others find it does not work for them and causes many side-effects.

If you would like to find out more about this study then please click here.

The INCOGNITO Trial: Investigating COPD Lung Infections with Different Inhalers. NHS Tayside & NHS Greater Glasgow and Clyde.

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide and a major cause of morbidity in the UK. Patients with COPD are frequently prescribed inhalers which contain steroids or bronchodilators to help reduce symptoms. There are a number of different treatments available for patients with COPD, however some treatments that are of benefit to one group of patients may produce side effects in others.

This trial wants to compare two different inhalers that are both already in use for treating COPD. The researchers believe that the two inhalers will have different effects on the bacteria that live in the lungs and inflammation in the lungs. If this is the case, it means that future treatment could be much more effective as doctors will be able to match the right inhaler to the right patient by measuring their levels of inflammation at the start.

If you would like to read more about this study then please click here.

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For more information contact us at SHARE@dundee.ac.uk